|The 14.3.3 sigma sfn (Catalog #MBS839117) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The 14.3.3 sigma antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s 14.3.3 sigma can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Western Blot (WB).
IHC: 5 ug/ml
WB: 13 ug/ml. Researchers should empirically determine the suitability of the 14.3.3 sigma sfn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The 14.3.3 sigma sfn product has the following accession number(s) (GI #5454052) (NCBI Accession #NP_006133.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Rabbit polyclonal Human 14.3.3 sigma antibody.
Source Note: Serum
Biological Significance: 14-3-3 sigma, has been shown to be regulated by p53 and to play a role in the G2Mphase checkpoint. 14-3-3 sigma was cloned by expression cloning through cyclin dependent kinase 2 (CDK2) association. 14-3-3 sigma shares cyclinCDK2 binding motifs with different cell cycle regulators, including p107, p130, p21 (CIP1), p27 (KIP1), and p57 (KIP2), and is associated with cyclin. Immunogen: 14-3-3 sigma antibody was raised in rabbit using a synthetic peptide for Nterminus portion of Human 14-3-3 gamma as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing 14.3.3 sigma are readily searchable from our website. Different antibodies against the same target such as 14.3.3 sigma may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. 14.3.3 sigma also interacts with the following gene(s): AKT1, BAD, CDC25B, CDK1, MAPK1, TP53, TSC2, UBC. The following patways have been known to be associated with this gene. Adenocarcinoma, Breast Neoplasms, Carcinoma, Carcinoma, Squamous Cell, Disease Models, Animal, Inflammation, Lung Neoplasms, Necrosis, Neoplasm Metastasis, Prostatic Neoplasms are some of the diseases may be linked to 14.3.3 sigma antibody. Blood, Brain, Liver, Lung, Lymph Node, Muscle, Nerve, Prostate, Skin, Thyroid tissues are correlated with this protein.