anti-AARS antibody product blog
Tags: Antibody; Polyclonal Antibody; AARS; anti-AARS antibody;
The AARS aars (Catalog #MBS9401743) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AARS Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s AARS can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC).Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100. Researchers should empirically determine the suitability of the AARS aars for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The AARS aars product has the following accession number(s) (GI #109148542) (NCBI Accession #NP_001596.2) (Uniprot Accession #P49588). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the AARS Antibody with the following immunoassay(s):
Testing Data (Gel: 8%SDS-PAGE Lysate: 40ug K562 cell Primary antibody: 1/283 dilution Secondary antibody dilution: 1/8000 Exposure time: 1 minute)
Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human brain cancer tissue using at dilution 1/50.)
The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E Coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure.
Immunogen Type: Peptide
Immunogen Description: Synthetic peptide corresponding to residues near the N terminal of human alanyl-tRNA synthetase. Target Name: AARS. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing AARS are readily searchable from our website. Different antibodies against the same target such as AARS may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Cardiomyopathies, Cardiovascular Diseases, Heart Diseases, Hypertension, Inflammation, Kidney Diseases, Liver Diseases, Lung Diseases, Myocardial Infarction, Nervous System Diseases are some of the diseases may be linked to AARS Antibody.