|The ABCD1 abcd1 (Catalog #MBS644513) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ABCD1, ID (ABCD1, ALD, ATP-binding cassette sub-family D member 1, Adrenoleukodystrophy protein) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s ABCD1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC).
Suitable for use in Western Blot and Immunohistochemistry.
Dilution: Immunohistochemistry (Paraffin): 5ug/ml. Researchers should empirically determine the suitability of the ABCD1 abcd1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ABCD1 abcd1 product has the following accession number(s) (GI #7262393) (NCBI Accession #NP_000024.2) (Uniprot Accession #P33897). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system.
Immunogen: Recombinant corresponding to human ABCD1. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ABCD1 are readily searchable from our website. Different antibodies against the same target such as ABCD1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Adrenal Gland, Blood, Bone, Brain, Kidney, Liver, Muscle, Nerve, Skin, Testis tissues are correlated with this protein. Abnormalities, Multiple, Adrenoleukodystrophy, Carcinoma, Cognition Disorders, Fatty Liver, Inflammation, Liver Diseases, Necrosis, Nerve Degeneration, Nervous System Diseases are some of the diseases may be linked to ABCD1, ID (ABCD1, ALD, ATP-binding cassette sub-family D member 1, Adrenoleukodystrophy protein).