|The ABCG1 abcg1 (Catalog #MBS129616) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ABCG1 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s ABCG1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC).
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200. Researchers should empirically determine the suitability of the ABCG1 abcg1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ABCG1 abcg1 product has the following accession number(s) (GI #17433715) (NCBI Accession #P45844.3) (Uniprot Accession #P45844). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the ABCG1 Polyclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of extracts of various cell lines, using ABCG1 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 90s.)
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified.
Immunogen: Recombinant Protein. Immunogen: Recombinant protein of human ABCG1
Calculated Molecular Weight: 76kDa. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ABCG1 are readily searchable from our website. Different antibodies against the same target such as ABCG1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Atherosclerosis, Cardiovascular Diseases, Dyslipidemias, Fatty Liver, Hypercholesterolemia, Hyperlipidemias, Inflammation, Liver Diseases, Necrosis, Nervous System Diseases are some of the diseases may be linked to ABCG1 Polyclonal Antibody. Blood, Brain, Connective Tissue, Intestine, Kidney, Liver, Lung, Muscle, Pancreas, Spleen tissues are correlated with this protein. The following patways have been known to be associated with this gene.