|The ABCG5 abcg5 (Catalog #MBS9409003) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ABCG5 Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s ABCG5 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC).
Immunohistochemistry: 1:25-1:100. Researchers should empirically determine the suitability of the ABCG5 abcg5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ABCG5 abcg5 product has the following accession number(s) (GI #11967969) (NCBI Accession #NP_071881.1) (Uniprot Accession #Q9H222). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the ABCG5 Antibody with the following immunoassay(s):
Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using at dilution 1/20.)
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia.
Immunogen Type: Peptide
Immunogen Description: Synthetic peptide corresponding to residues near the N terminal of human ATP-binding cassette, sub-family G (WHITE), member 5. Target Name: ABCG5. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ABCG5 are readily searchable from our website. Different antibodies against the same target such as ABCG5 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. ABCG5 also interacts with the following gene(s): ABCC6, ABCG8, CYP7A1, LDLR, NPC1L1, NR1H2, NR1H3, SCARB1, SREBF1, SREBF2. Atherosclerosis, Cardiovascular Diseases, Coronary Disease, Dyslipidemias, Fatty Liver, Heart Diseases, Hyperlipidemias, Lipid Metabolism, Inborn Errors, Liver Diseases, Sitosterolemia are some of the diseases may be linked to ABCG5 Antibody.