|The ABI2 abi2 (Catalog #MBS176106) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-ABI2 antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s ABI2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the ABI2 abi2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ABI2 abi2 product has the following accession number(s) (GI #50400673) (NCBI Accession #Q9NYB9.1) (Uniprot Accession #Q9NYB9). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-ABI2 antibody with the following immunoassay(s):
Western Blot (WB) (Anti-ABI2 antibody, Western blotting
Lane 1: Rat Brain Tissue Lysate
Lane 2: Human Placenta Tissue Lysate
Lane 3: MCF-7 Cell Lysate
Lane 4: HELA Cell Lysate
Lane 5: JURKAT Cell Lysate)
Description: Rabbit IgG polyclonal antibody for Abl interactor 2(ABI2) detection. Tested with WB in Human, Mouse, Rat.
Background: ABI2(ABL Interactor 2), is a protein that in humans is encoded by the ABI2 gene. By analysis of a YAC and a BAC, Machado et al.(2000) mapped the ABI2 gene to 2q31-q33. ABI2 possesses a basic N terminus with homology to a homeodomain protein; a central serine-rich region; 3 PEST sequences, which are implicated in susceptibility to protein degradation; several proline-rich stretches; and an acidic C terminus with multiple phosphorylation sites and an SH3 domain. Dai and Pendergast(1995) suggested that the ABI proteins may function to coordinate the cytoplasmic and nuclear functions of the ABL1 tyrosine kinase.
Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human ABI2 (158-173aa RFKVSTQNMKMGGLPR), identical to the related mouse and rat sequences. Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ABI2 are readily searchable from our website. Different antibodies against the same target such as ABI2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Bone, Brain, Embryonic Tissue, Eye, Heart, Muscle, Nerve, Thyroid, Vascular tissues are correlated with this protein.