anti-ACAT1 antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-ACAT1 antibody; ACAT1;
The ACAT1 acat1 (Catalog #MBS6002453) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ACAT1, ID (Acetyl-CoA Acetyltransferase, Mitochondrial, Acetoacetyl-CoA Thiolase, T2, ACAT, MAT) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s ACAT1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC).Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Dilution: ELISA: 1:40,000
Western Blot: 1:500-1:1000
Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml. Researchers should empirically determine the suitability of the ACAT1 acat1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ACAT1 acat1 product has the following accession number(s) (GI #4557237) (NCBI Accession #NP_000010.1) (Uniprot Accession #P24752). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the ACAT1, ID (Acetyl-CoA Acetyltransferase, Mitochondrial, Acetoacetyl-CoA Thiolase, T2, ACAT, MAT) with the following immunoassay(s):
Immunohistochemistry (IHC) (Human Liver, Hephatocytes: Formalin-Fixed, Paraffin-Embedded (FFPE))
Western Blot (WB) (Western blot analysis of extracts from HepG2/Jurkat/293/A549 cells, using ACAT1 antibody. The lane on the right is treated with the synthesized peptide.)
The ACAT1 mRNA encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. The ACAT gene spans approximately 27kb and contains 12 exons interrupted by 11 introns. Defects in this gene are associated with the alpha-methylacetoaceticaciduria disorder, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone.
Immunogen: Synthetic peptide corresponding to human ACAT1. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ACAT1 are readily searchable from our website. Different antibodies against the same target such as ACAT1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Adipose Tissue, Blood, Bone, Brain, Heart, Intestine, Kidney, Liver, Muscle, Ovary tissues are correlated with this protein. Atherosclerosis, Cardiovascular Diseases, Dyslipidemias, Fatty Liver, Hypercholesterolemia, Hyperlipidemias, Hypertension, Liver Diseases, Neoplasms, Nervous System Diseases are some of the diseases may be linked to ACAT1, ID (Acetyl-CoA Acetyltransferase, Mitochondrial, Acetoacetyl-CoA Thiolase, T2, ACAT, MAT).