anti-ACBD3 antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-ACBD3 antibody; ACBD3; GOLPH1;
The ACBD3 acbd3 (Catalog #MBS150942) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GOLPH1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s GOLPH1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB).GOLPH1 antibody can be used for detection of GOLPH1 by Western blot at 1 - 2 mug/mL. Researchers should empirically determine the suitability of the ACBD3 acbd3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ACBD3 acbd3 product has the following accession number(s) (GI #119590181) (NCBI Accession #EAW69775) (Uniprot Accession #Q9H3P7). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the GOLPH1 Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of GOLPH1 in K562 cell lysate with GOLPH1 antibody at (A) 1 and (B) 2 μg/mL.)
GOLPH1 Antibody: GOLPH1, also known as GCP60, was initially identified as a Golgi protein that can interact with the integral membrane protein giantin and is thought to be involved in the maintenance of the Golgi structure. GOLPH1 has also been shown to interact with other Golgi proteins such as Golgin-160, a Golgi protein that can be cleaved by caspases-2, -3, and -7, leading to the nuclear localization of Golgin-160. GOLPH1 interaction with the Golgin-160 fragments is stronger than that with the intact Golgin-160, with its interaction regulated by the oxidation state of Cys-463 within GOLPH1, suggesting that the nuclear localization of the caspase-cleaved Golgin-160 fragments is a highly coordinated event. GOLPH1 has also been found to interact with Numb, a cytosolic signaling protein that mediates asymetric cell division of neural progenitor cells to a daughter progenitor cell and a neuron, suggesting that Golgi fragmentation and reconstitution during the cell cycle differentially regulate Numb signaling through changes in GOLPH1 subcellular distribution and may couple cell fate with cell cycle progression.
Conjugate: Unconjugated
Immunogen: GOLPH1 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human GOLPH1.
Buffer: GOLPH1 Antibody is supplied in PBS containing 0.02% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ACBD3 are readily searchable from our website. Different antibodies against the same target such as ACBD3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.