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anti-ACE antibody product blog

Posted on 2017-03-03 03:31:49 by mybiosource_staff
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Tags: Antibody; ACE; Polyclonal Antibody; anti-ACE antibody; Angiotensin Converting Enzyme 1;
The ACE ace (Catalog #MBS177022) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Angiotensin Converting Enzyme 1 antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Angiotensin Converting Enzyme 1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin. Researchers should empirically determine the suitability of the ACE ace for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The ACE ace product has the following accession number(s) (GI #113045) (NCBI Accession #P12821.1) (Uniprot Accession #P12821). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-Angiotensin Converting Enzyme 1 antibody with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti- ACE antibody, MBS177022, IHC(P)
IHC(P): Human Placenta Tissue )
Immunohistochemistry (IHC) ACE.

Immunohistochemistry (IHC) (Anti- ACE antibody, MBS177022, IHC(P)
IHC(P): Human Prostatic Cancer Tissue )
Immunohistochemistry (IHC) ACE.

Western Blot (WB) (Anti- ACE antibody, MBS177022, Western blotting
All lanes: Anti Angiotensin Converting Enzyme 1 (MBS177022) at 0.5ug/ml
Lane 1: HELA Whole Cell Lysate at 40ug
Lane 2: A549 Whole Cell Lysate at 40ug
Lane 3: 22RV1 Whole Cell Lysate at 40ug
Predicted bind size: 150KD
Observed bind size: 150KD )
Western Blot (WB) ACE.

Description: Rabbit IgG polyclonal antibody for Angiotensin-converting enzyme(ACE) detection. Tested with WB, IHC-P in Human.
Background: Angiotensin I converting enzyme(ACE), also called DCP or CD143, is a zinc-containing dipeptidyl carboxypeptidase widely distributed in mammalian tissues and is though to play a critical role in blood pressure regulation. ACE gene is mapped to 17q23.3. This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human Angiotensin Converting Enzyme 1 (702-715aa TQARKFDVNQLQNT). Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ACE are readily searchable from our website. Different antibodies against the same target such as ACE may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.
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