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anti-ACO1 antibody product blog

Posted on 2017-07-09 11:47:40 by mybiosource_staff
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Tags: Antibody; Polyclonal Antibody; ACO1; anti-ACO1 antibody;
The ACO1 aco1 (Catalog #MBS9217191) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ACO1 Antibody (Center) reacts with Human, Mouse, Rat; Predicted Reactivity: Bovine, Chicken and may cross-react with other species as described in the data sheet. MyBioSource\'s ACO1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA).
WB:~~1:2000. Researchers should empirically determine the suitability of the ACO1 aco1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The ACO1 aco1 product has the following accession number(s) (GI #507834063) (NCBI Accession #NP_001265281.1) (Uniprot Accession #P21399). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the ACO1 Antibody (Center) with the following immunoassay(s):
Western Blot (WB) (All lanes : Anti-ACO1 Antibody (Center) at 1:2000 dilution
Lane 1: human kidney lysate
Lane 2: human liver lysate
Lane 3: U-2OS whole cell lysate
Lane 4: A431 whole cell lysate
Lane 5: mouse kidney lysate
Lysates/proteins at 20 ug per lane.
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.
Predicted band size : 98 kDa
Blocking/Dilution buffer: 5% NFDM/TBST.)
Western Blot (WB) ACO1.

Iron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Functions as mRNA binding protein that regulates uptake, sequestration and utilization of iron when cellular iron levels are low. Binds to iron-responsive elements (IRES) in target mRNA species when iron levels are low. Binding of a 4Fe-4S cluster precludes RNA binding.

Subtitle: Purified Rabbit Polyclonal Antibody (Pab)
Cellular Location: Cytoplasm. Antigen Type: Synthesized Peptide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ACO1 are readily searchable from our website. Different antibodies against the same target such as ACO1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Brain, Embryonic Tissue, Eye, Kidney, Liver, Lung, Muscle, Skin, Vascular tissues are correlated with this protein. Anemia, Brain Diseases, Fatty Liver, Fibrosis, Inflammation, Kidney Diseases, Lung Diseases, Lung Neoplasms, Nerve Degeneration, Nervous System Diseases are some of the diseases may be linked to ACO1 Antibody (Center). The following patways have been known to be associated with this gene. ACO1 also interacts with the following gene(s): ACO2, FTH1, IDH1, IDH2.
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