|The ACOT2 acot2 (Catalog #MBS2525347) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ACOT2 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s ACOT2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC).
IHC: 1:15-1:50. Researchers should empirically determine the suitability of the ACOT2 acot2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ACOT2 acot2 product has the following accession number(s) (GI #148727286) (NCBI Accession #NP_006812.3). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the ACOT2 Polyclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of MCF7 cell using ACOT2 Polyclonal Antibody at dilution of 1:150)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human thyroid cancer using ACOT2 Polyclonal Antibody at dilution of 1:15)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human lung cancer using ACOT2 Polyclonal Antibody at dilution of 1:15)
This gene encodes a member of the acyl-CoA thioesterase protein family, and is one of four acyl-CoA hydrolase genes located in a cluster on chromosome 14. Alternative splicing results in multiple transcript variants. Acyl-CoA thioesterases, such as ACOT2, are a group of enzymes that hydrolyze Coenzyme A (CoA) esters, such as acyl-CoAs, bile CoAs, and CoA esters of prostaglandins, to the corresponding free acid and CoA. ACOT2 shows high acyl-CoA thioesterase activity on medium- and long-chain acyl-CoAs, with an optimal pH of 8. 5. It is most active on myristoyl-CoA but also shows high activity on palmitoyl-CoA, stearoyl-CoA, and arachidoyl-CoA.
Immunogen: Recombinant protein of human ACOT2
Calculated Molecular Weight: 53kDa. Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ACOT2 are readily searchable from our website. Different antibodies against the same target such as ACOT2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Adipose Tissue, Adrenal Gland, Blood, Brain, Connective Tissue, Heart, Liver, Muscle, Ovary, Testis tissues are correlated with this protein. Abnormalities, Drug-Induced, Disease Models, Animal, Fatty Liver, Hyperplasia, Weight Gain, Weight Loss are some of the diseases may be linked to ACOT2 Polyclonal Antibody.