anti-ACR antibody product blog
Tags: Antibody; Polyclonal Antibody; Acrosin; anti-ACR antibody; ACR;
The ACR acr (Catalog #MBS248509) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human Acrosin reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Acrosin can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB).IHC-P (1:50 - 1:100), WB (1:1000). Researchers should empirically determine the suitability of the ACR acr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ACR acr product has the following accession number(s) (GI #148613878) (NCBI Accession #NP_001088.2) (Uniprot Accession #P10323). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit Polyclonal to Human Acrosin with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-Acrosin antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC) (Formalin-fixed and paraffin-embedded human testis tissue reacted with ACR Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.)
Western Blot (WB) (Western blot of ACR Antibody (C-term) in Jurkat cell line lysates (35 ug/lane). ACR (arrow) was detected using the purified Pab.)
Acrosin is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis.
Target Species: Human
Immunogen Description: KLH-conjugated synthetic peptide from C-terminal region of human ACR. Immunogen Type: Synthetic peptide
Immunogen: Acrosin antibody was raised against kLH-conjugated synthetic peptide from C-terminal region of human ACR.
Antigen Modification: aa 387-416. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ACR are readily searchable from our website. Different antibodies against the same target such as ACR may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain, Ovary, Testis tissues are correlated with this protein. ACR also interacts with the following gene(s): PELO, SPAM1, ZP3.