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anti-ADAMTS5 antibody product blog

Posted on 2015-08-31 02:55:38 by mybiosource_staff
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Tags: Antibody; Polyclonal Antibody; ADAMTS5; anti-ADAMTS5 antibody;
The ADAMTS5 adamts5 (Catalog #MBS2528251) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ADAMTS5 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s ADAMTS5 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC).
IHC: 1:25-1:100. Researchers should empirically determine the suitability of the ADAMTS5 adamts5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The ADAMTS5 adamts5 product has the following accession number(s) (GI #195539372) (NCBI Accession #NP_008969.2). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the ADAMTS5 Polyclonal Antibody with the following immunoassay(s):
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human lung cancer using ADAMTS5 Polyclonal Antibody at dilution of 1:10)
Immunohistochemistry (IHC) ADAMTS5.

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs and functions as aggrecanase to cleave aggrecan, a major proteoglycan of cartilage.

Immunogen: Synthetic peptide of human ADAMTS5. Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ADAMTS5 are readily searchable from our website. Different antibodies against the same target such as ADAMTS5 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. ADAMTS5 also interacts with the following gene(s): ACAN, FGF2, FURIN, MMP13, MMP3, RUNX2, SDC4, TIMP3. Brain, Connective Tissue, Embryonic Tissue, Eye, Heart, Liver, Lung, Muscle, Placenta, Skin tissues are correlated with this protein. The following patways have been known to be associated with this gene. Brain Diseases, Central Nervous System Diseases, Disease Models, Animal, Fibrosis, Heart Diseases, Hyperplasia, Inflammation, Necrosis, Nervous System Diseases, Weight Loss are some of the diseases may be linked to ADAMTS5 Polyclonal Antibody.
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