anti-ADIPOQ antibody product blog
Tags: Antibody; Adiponectin; Polyclonal Antibody; anti-ADIPOQ antibody; ADIPOQ;
The ADIPOQ adipoq (Catalog #MBS176872) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Adiponectin antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s Adiponectin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunohistochemistry (IHC) Formalin, ELISA (EIA). Researchers should empirically determine the suitability of the ADIPOQ adipoq for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The ADIPOQ adipoq product has the following accession number(s) (GI #2493789) (NCBI Accession #Q15848.1) (Uniprot Accession #Q15848). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-Adiponectin antibody with the following immunoassay(s):
Western Blot (WB) (Anti-Adiponectin antibody, MBS176872, Western blotting
WB: Rat Heart Tissue Lysate )
Western Blot (WB) (Anti-Adiponectin antibody, MBS176872, Western blotting
Recombinant Protein Detection Source: E.coli derived -recombinant Human ADIPOQ, 44.4 KD(162aa tag+ M1-N244)
Lane 1: Recombinant Human ADIPOQ Protein 10ng
Lane 2: Recombinant Human ADIPOQ Protein 5ng
Lane 3: Recombinant Human ADIPOQ Protein 2.5ng )
Immunohistochemistry (IHC) (Anti-Adiponectin antibody, MBS176872, IHC(P)
IHC(P): Rat Kidney Tissue )
Immunohistochemistry (IHC) (Anti-Adiponectin antibody, MBS176872, IHC(P)
IHC(P): Mouse Kidney Tissue )
Immunohistochemistry (IHC) (Anti-Adiponectin antibody, MBS176872, IHC(F)
IHC(F): Rat Liver Tissue )
Immunohistochemistry (IHC) (Anti-Adiponectin antibody, MBS176872, IHC(P)
IHC(P): Human Placenta Tissue )
Description: Rabbit IgG polyclonal antibody for Adiponectin(ADIPOQ) detection. Tested with WB, IHC-P, IHC-F, ELISA in Human, Mouse, Rat.
Background: ADIPOQ(Adipocyte-, C1q-, and Collagen Domain-Containing), also known as APM1, ADPN or ACDC, is a protein which in humans is encoded by the ADIPOQ gene. Using FISH, Das et al.(2001) mapped the mouse Acrp30 gene to chromosome 16 in a region showing homology of synteny with human 3q27. By RNase protection and Western blot analysis, Schaffler et al.(1999) showed that APM1 is expressed by differentiated adipocytes as a 33-kD protein that is also detectable in serum. By sequence comparisons, they found links between APM1 and TNF family ligands as well as to cytokines expressed by T cells. Adiponectin is a protein hormone that modulates a number of metabolic processes, including glucose regulation and fatty acid oxidation. Adiponectin is exclusively secreted from adipose tissue(and also from the placenta in pregnancy) into the bloodstream and is very abundant in plasma relative to many hormones.
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human ADIPOQ (224-244aa LYADNDNDSTFTGFLLYHDTN), different from the related mouse and rat sequences by one amino acid.