|The ADORA2B adora2b (Catalog #MBS244415) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human ADORA2B/Adenosine A2B Receptor reacts with Gibbon, Gorilla, Human
Predicted Reactivity: Monkey, Horse (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. MyBioSource\'s ADORA2B/Adenosine A2B Receptor can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin).
IHC-P (10 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after proteinase K antigen retrieval. After incubation with the primary antibody, slides were incubate.. Researchers should empirically determine the suitability of the ADORA2B adora2b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ADORA2B adora2b product has the following accession number(s) (GI #4501951) (NCBI Accession #NP_000667.1) (Uniprot Accession #P29275). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit Polyclonal to Human ADORA2B/Adenosine A2B Receptor with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-Adenosine A2b Receptor antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC) (Anti-Adenosine A2b Receptor antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
The A2b Adenosine Receptor is a target of theophylline and enprofylline in the treatment of asthma. In lung mast cells, A2b receptors are associated with the release of inflammatory mediators. They can also bind the axonal chemoattractant netrin-1 (Corset et al., 2000). Netrin-1-dependent outgrowth of axons in the dorsal spinal cord directly involves the adenosine A2b receptor and may involve a receptor complex containing the DCC (deleted in colorectal cancer) protein and adenosine A2b receptor.
Target Species: Human
Immunogen Description: Synthetic 16 amino acid peptide from internal region of human Adenosine A2b Receptor. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Monkey, Marmoset, Horse (94%); Rabbit (88%); Dog (81%). Immunogen Type: Synthetic peptide
Immunogen: ADORA2B/Adenosine A2B Receptor antibody was raised against synthetic 16 amino acid peptide from internal region of human Adenosine A2b Receptor. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Monkey, Marmoset, Horse (94%); Rabbit (88%); Dog (81%).
Antigen Modification: Internal. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ADORA2B are readily searchable from our website. Different antibodies against the same target such as ADORA2B may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.