anti-ADRB2 antibody product blog
Tags: Antibody; ADRB2; anti-ADRB2 antibody; Polyclonal Antibody;
The ADRB2 adrb2 (Catalog #MBS2521589) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ADRB2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s ADRB2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC).WB: 1:500-1:2000
IHC: 1:50-1:200. Researchers should empirically determine the suitability of the ADRB2 adrb2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ADRB2 adrb2 product has the following accession number(s) (GI #608785131) (NCBI Accession #AHW56402.1) (Uniprot Accession #P07550). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the ADRB2 Antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of Mouse heart tissue using ADRB2 Polyclonal Antibody at dilution of 1:1000)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human heart tissue slide using ADRB2 Polyclonal Antibody at dilution of 1:50)
Beta-2 adrenergic receptor (ADRB2), a member of the G protein-coupled receptor (GPCR) family, binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine. ADRB2 is directly linked to one of its final effectors, the class C L-type Ca2+ channel, Cav1.2 (PMID: 11441182). This receptor-channel complex also contains a G protein, an adenylyl cyclase, cyclic adenosine monophosphate-dependent protein kinase (PKA), and a counteracting phosphatase, PP2A. Different polymorphic forms, point mutations, and/or downregulation of the gene of ADRB2 are associated with nocturnal asthma, obesity and type 2 diabetes. This antibody detects ADRB2 with an apparent molecular weight of 50-55 kDa as has been shown by some researches (PMID: 25348166; 12502786; 29232706; 23984976; 19584355).
Immunogen: ADRB2 fusion protein Ag3715. Note: Centrifuge before opening to ensure complete recovery of vial contents. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ADRB2 are readily searchable from our website. Different antibodies against the same target such as ADRB2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Asthma, Cardiovascular Diseases, Heart Diseases, Heart Failure, Hypertension, Inflammation, Lung Diseases, Myocardial Ischemia, Nervous System Diseases, Obesity are some of the diseases may be linked to ADRB2 Antibody. Blood, Brain, Connective Tissue, Eye, Heart, Kidney, Liver, Lung, Trachea, Uterus tissues are correlated with this protein.