|The ADRB3 adrb3 (Catalog #MBS247623) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human ADRB3 reacts with Human
Predicted Reactivity: Gorilla, Monkey (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. MyBioSource\'s ADRB3 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin).
IHC-P (20 - 40 ug/ml). Researchers should empirically determine the suitability of the ADRB3 adrb3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ADRB3 adrb3 product has the following accession number(s) (GI #4557267) (NCBI Accession #NP_000016.1) (Uniprot Accession #P13945). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit Polyclonal to Human ADRB3 with the following immunoassay(s):
Immunohistochemistry (IHC) (Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunohistochemistry (IHC) (Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE))
The Beta-3 Adrenoceptor (ADRB3) is an Adrenergic Receptor that stimulates lipolysis and increases fatty acids in the blood. Stimulation of the beta-3 adrenoceptor leads to lipolysis in white adipocytes and nonshivering thermogenesis in brown fat. The beta-3 adrenoceptor has also been suggested to affect the physiological control of cardiac and vascular contractility; beta-3 adrenoceptor stimulation decreases cardiac contractility through activation of a nitric oxide synthase pathway.
Target Species: Human
Immunogen Description: Synthetic 18 amino acid peptide from C-terminus of human ADRB3. Percent identity with other species by BLAST analysis: Human (100%); Gorilla, Monkey (94%). Immunogen Type: Synthetic peptide
Immunogen: ADRB3 antibody was raised against synthetic 18 amino acid peptide from C-terminus of human ADRB3. Percent identity with other species by BLAST analysis: Human (100%); Gorilla, Monkey (94%).
Antigen Modification: C-Terminus. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ADRB3 are readily searchable from our website. Different antibodies against the same target such as ADRB3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. ADRB3 also interacts with the following gene(s): ADRB2, CRH, GNAS, LEP, MC4R, POMC, UCP1. Heart Diseases, Heart Failure, Hyperglycemia, Hypertension, Hypertrophy, Inflammation, Myocardial Infarction, Myocardial Ischemia, Necrosis, Obesity are some of the diseases may be linked to Rabbit Polyclonal to Human ADRB3.