anti-AFAP1 antibody product blog
Tags: Antibody; Polyclonal Antibody; AFAP1; anti-AFAP1 antibody; AFAP1-Y451;
The AFAP1 afap1 (Catalog #MBS9207578) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AFAP1-Y451 Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s AFAP1-Y451 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA).WB~~1:1000. Researchers should empirically determine the suitability of the AFAP1 afap1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The AFAP1 afap1 product has the following accession number(s) (GI #197382472) (NCBI Accession #NP_001128119.1) (Uniprot Accession #Q8N556). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the AFAP1-Y451 Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of lysates from Hela, MCF-7, MDA-MB-231, MDA-MB-453 cell line (from left to right), using AFAP1-Y451. MBS9207578 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.)
Can cross-link actin filaments into both network and bundle structures (By similarity). May modulate changes in actin filament integrity and induce lamellipodia formation. May function as an adapter molecule that links other proteins, such as SRC and PKC to the actin cytoskeleton. Seems to play a role in the development and progression of prostate adenocarcinoma by regulating cell-matrix adhesions and migration in the cancer cells.
Crown Antibody: Yes. Antigen Source: HUMAN. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing AFAP1 are readily searchable from our website. Different antibodies against the same target such as AFAP1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain, Ear, Esophagus, Eye, Mammary Gland, Muscle, Pancreas, Prostate, Vascular tissues are correlated with this protein. AFAP1 also interacts with the following gene(s): ACTA1, SRC. Nervous System Diseases are some of the diseases may be linked to AFAP1-Y451 Antibody.