|The AGER ager (Catalog #MBS2520269) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AGER Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s AGER can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC).
IHC: 1:100-1:300. Researchers should empirically determine the suitability of the AGER ager for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The AGER ager product has the following accession number(s) (GI #332800988) (NCBI Accession #NP_001193895.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the AGER Polyclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of Human kidney and Mouse brain tissue using AGER Polyclonal Antibody at dilution of 1:750)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human gastic cancer using AGER Polyclonal Antibody at dilution of 1:70)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human liver cancer using AGER Polyclonal Antibody at dilution of 1:70)
The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer\'s disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene.
Immunogen: Recombinant protein of human AGER
Calculated Molecular Weight: 43kDa. Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing AGER are readily searchable from our website. Different antibodies against the same target such as AGER may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. AGER also interacts with the following gene(s): CCL2, CRP, HMG1, HMGB1, MMP2, RAGE, S100A12, S100B. Atherosclerosis, Cardiovascular Diseases, Fibrosis, Heart Diseases, Inflammation, Liver Diseases, Lung Diseases, Lung Neoplasms, Necrosis, Prenatal Exposure Delayed Effects are some of the diseases may be linked to AGER Polyclonal Antibody. The following patways have been known to be associated with this gene.