anti-Agpt2 antibody product blog
Tags: Antibody; Polyclonal Antibody; Angiopoietin-2; anti-Agpt2 antibody; Agpt2;
The Agpt2 angpt2 (Catalog #MBS1488996) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-mouse Angiopoietin-2 polyclonal Antibody reacts with Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s Angiopoietin-2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the Agpt2 angpt2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The Agpt2 angpt2 product has the following accession number(s) (GI #31982508) (NCBI Accession #NP_031452.2) (Uniprot Accession #O35608). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit anti-mouse Angiopoietin-2 polyclonal Antibody with the following immunoassay(s):
Western Blot (WB) (All lanes: Angiopoietin-2 antibody at 2ug/ml+mouse lungs tissue
Secondary
Goat polyclonal to Rabbit IgG at 1/10000 dilution
Predicted band size: 57kDa
Observed band size: 57kDa
)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded mouse kidney using MBS1488996 at dilution of 1:50)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded mouse placenta using MBS1488996 at dilution of 1:20)
Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.
Storage Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate: Non-conjugated. Immunogen: Recombinant mouse Angiopoietin-2 protein. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Agpt2 are readily searchable from our website. Different antibodies against the same target such as Agpt2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Agpt2 also interacts with the following gene(s): Ets1, Flt1, Flt4, Foxo1, Kdr, Mmp2, Pdgfrb, Tek, Tie1, Vegfa. The following patways have been known to be associated with this gene. Bone Marrow, Brain, Embryonic Tissue, Eye, Kidney, Lung, Muscle, Ovary, Skin, Uterus tissues are correlated with this protein. Cardiovascular Diseases, Disease Models, Animal, Heart Diseases, Inflammation, Kidney Diseases, Liver Diseases, Liver Neoplasms, Necrosis, Neoplasm Metastasis, Neoplasms, Experimental are some of the diseases may be linked to Rabbit anti-mouse Angiopoietin-2 polyclonal Antibody.