anti-AGT antibody product blog
Tags: Antibody; AGT; Polyclonal Antibody; anti-AGT antibody; AGT / Angiotensinogen;
The AGT agt (Catalog #MBS244099) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human AGT / Angiotensinogen reacts with Gibbon, Chimpanzee, Gorilla, Human, Monkey, Orangutan and may cross-react with other species as described in the data sheet. MyBioSource\'s AGT / Angiotensinogen can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin).IHC-P (2.5 - 5 ug/ml). Researchers should empirically determine the suitability of the AGT agt for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The AGT agt product has the following accession number(s) (GI #4557287) (NCBI Accession #NP_000020.1) (Uniprot Accession #P01019). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit Polyclonal to Human AGT / Angiotensinogen with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-AGT / Angiotensinogen antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
The human AGT gene product, pre-angiotensinogen, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. Human pre-angiotensinogen is encoded by two mRNAs that differ only in the length of the 3\'-untranslated region due to postulated use of two polyadenylation sites.
Target Species: Human
Immunogen Description: Synthetic 12 amino acid peptide from internal region of human AGT / Angiotensinogen. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset (100%). Immunogen Type: Synthetic peptide
Immunogen: AGT / Angiotensinogen antibody was raised against synthetic 12 amino acid peptide from internal region of human AGT / Angiotensinogen. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset (100%).
Antigen Modification: Internal. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing AGT are readily searchable from our website. Different antibodies against the same target such as AGT may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. AGT also interacts with the following gene(s): ACE, ACE2, AGTR1, AGTR2, IL6, INS, REN, TGFB1. Atherosclerosis, Cardiovascular Diseases, Heart Diseases, Hypertension, Hypertension, Renal, Hypertrophy, Kidney Diseases, Myocardial Infarction, Myocardial Ischemia, Proteinuria are some of the diseases may be linked to Rabbit Polyclonal to Human AGT / Angiotensinogen.