|The AGTR1 agtr1 (Catalog #MBS178133) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Anti-AGTR1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s AGTR1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin.
Tested Species: Hu, Ms
Immunohistochemistry (IHC) Paraffin:
Tested Species: Hu
Antigen Retrieval: By Heat
Tested Species: In-house tested species with positive results.
By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Other applications have not been tested.
Optimal dilutions shold be determined by end users. Researchers should empirically determine the suitability of the AGTR1 agtr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The AGTR1 agtr1 product has the following accession number(s) (GI #4501997) (NCBI Accession #NP_000676.1) (Uniprot Accession #P30556). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-AGTR1 Antibody with the following immunoassay(s):
Western Blot (WB) (Anti- AGTR1 Picoband antibody, MBS178133, Western blotting
All lanes: Anti AGTR1 (MBS178133) at 0.5ug/ml
Lane 1: HELA Whole Cell Lysate at 40ug
Lane 2: HEPA Whole Cell Lysate at 40ug
Predicted bind size: 47KD
Observed bind size: 47KD )
Immunohistochemistry (IHC) (Anti- AGTR1 Picoband antibody, MBS178133, IHC(P)
IHC(P): Human Mammary Cancer Tissue )
Description: Rabbit IgG polyclonal antibody for Type-1 angiotensin II receptor(AGTR1) detection. Tested with WB, IHC-P in Human;Mouse.
Background: AGTR1 is known as Angiotensin II Type 1 Receptor. Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. And it acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. Moreover, this gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene.
Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human AGTR1 (1-28aa MILNSSTEDGIKRIQDDCPKAGRHNYIF), different from the related mouse and rat sequences by one amino acid.
Ig Type: Rabbit IgG.