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anti-AGXT antibody product blog

Posted on 2016-09-11 05:50:14 by mybiosource_staff
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Tags: Antibody; Polyclonal Antibody; anti-AGXT antibody; AGXT;
The AGXT agxt (Catalog #MBS9128283) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AGXT Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s AGXT can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).
WB 1:500 - 1:2000. Researchers should empirically determine the suitability of the AGXT agxt for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The AGXT agxt product has the following accession number(s) (GI #4557289) (NCBI Accession #NP_000021.1) (Uniprot Accession #P21549). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the AGXT Polyclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of extracts of various cell lines, using AGXT antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 60s.)
Western Blot (WB) AGXT.

This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria.

Immunogen: Recombinant Protein. Immunogen: Recombinant protein of human AGXT. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing AGXT are readily searchable from our website. Different antibodies against the same target such as AGXT may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Cardiovascular Diseases, Fatty Liver, Hypertension, Kidney Diseases, Liver Diseases, Neoplasms, Experimental, Nervous System Diseases, Neurotoxicity Syndromes, Poisoning, Primary hyperoxaluria type 1 are some of the diseases may be linked to AGXT Polyclonal Antibody. AGXT also interacts with the following gene(s): GRHPR. Blood, Brain, Intestine, Kidney, Liver tissues are correlated with this protein.
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