anti-AHR antibody product blog
Tags: Antibody; anti-AhR antibody; AhR; Polyclonal Antibody;
The AHR ahr (Catalog #MBS9201512) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AHR Antibody (Center) reacts with Human, mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s AHR can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA).WB~~1:500. Researchers should empirically determine the suitability of the AHR ahr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The AHR ahr product has the following accession number(s) (GI #4502003) (NCBI Accession #NP_001612.1) (Uniprot Accession #P35869). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the AHR Antibody (Center) with the following immunoassay(s):
Western Blot (WB) (All lanes : Anti-AHR Antibody (Center) at 1:500 dilution
Lane 1: Hela whole cell lysate
Lane 2: MCF-7 whole cell lysate
Lane 3: A549 whole cell lysate
Lane 4: PC-3 whole cell lysate
Lane 5: HepG2 whole cell lysate
Lane 6: C2C12 whole cell lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.
Predicted band size : 96 kDa
Blocking/Dilution buffer: 5% NFDM/TBST.)
AHR is a ligand-activated transcription factor
involved in the regulation of biological responses to planar
aromatic hydrocarbons. This receptor has been shown to regulate
xenobiotic-metabolizing enzymes such as cytochrome P450. Its
ligands included a variety of aromatic hydrocarbons. [provided by
RefSeq].
Function: Ligand-activated transcriptional activator.Binds to the XRE promoter region of genes itactivates (PubMed:10395741, PubMed:
Cellular Location: Cytoplasm{ECO:0000250|UniProtKB:P30561}. Nucleus {ECO:0000250|UniProtKB:P30561}. Note=Initially cytoplasmic; upon binding with ligand and interaction with a HSP90, it translocates to the nucleus{ECO:0000250|UniProtKB:P30561}
Tissue Location: Expressed in all tissues tested including blood, brain, heart, kidney, liver, lung, pancreas and skeletal muscle. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing AHR are readily searchable from our website. Different antibodies against the same target such as AHR may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.