anti-AIFM3 antibody product blog
Tags: Antibody; Polyclonal Antibody; AIFM3; anti-AIFM3 antibody;
The AIFM3 aifm3 (Catalog #MBS2525521) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AIFM3 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s AIFM3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC).WB: 1:200-1:1000
IHC: 1:50-1:200. Researchers should empirically determine the suitability of the AIFM3 aifm3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The AIFM3 aifm3 product has the following accession number(s) (GI #226437568) (NCBI Accession #NP_001139760.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the AIFM3 Polyclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of Hela cell using AIFM3 Polyclonal Antibody at dilution of 1:290)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human cervical cancer using AIFM3 Polyclonal Antibody at dilution of 1:50)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human thyroid cancer using AIFM3 Polyclonal Antibody at dilution of 1:50)
AIFL (apoptosis-inducing factor-like), also known as AIFM3 (apoptosis-inducing factor, mitochondrion-associated, 3), is a 605 amino acid protein that localizes to the mitochondrion and contains one rieske domain. Expressed ubiquitously in tissues including liver, thymus, ovary, bone marrow and cerebral cortex, AIFL functions to induce apoptosis, specifically through a caspase-dependent pathway, and may also play a role in the modulation of mitochondrial membrane potential. Multiple isoforms of AIFL exist due to alternative splicing events. The gene encoding AIFL maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome.
Immunogen: Recombinant protein of human AIFM3
Calculated Molecular Weight: 67kDa. Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing AIFM3 are readily searchable from our website. Different antibodies against the same target such as AIFM3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.