anti-AIM2 antibody product blog
Tags: Antibody; Polyclonal Antibody; AIM2; anti-AIM2 antibody;
The AIM2 aim2 (Catalog #MBS540955) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AIM2 Antibody BIOTIN-Conjugated reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s AIM2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB).Dot Blot: 1:10,000
ELISA: 1:10,000
Western Blot: 1:500. Researchers should empirically determine the suitability of the AIM2 aim2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The AIM2 aim2 product has the following accession number(s) (GI #4757734) (NCBI Accession #NP_004824) (Uniprot Accession #O14862). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
BIOTIN-Conjugated Interferon-inducible protein AIM2 Antibody
Innate immune response recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Tumor suppressor which may act by repressing NF-kappa-B transcriptional activity.
Immunogen: Synthetic peptide taken within amino acid region 240-340 on human AIM2 protein.
Expression: Expressed in spleen, small intestine, peripheral blood leukocytes and testis. Induced by IFNG/IFN-gamma and IFNB1/IFN-beta. Molecular Function: Apoptosis, Immunity, Inflammatory response, Innate Immunity
Structure: Self-associates; forms homodimers in response to cytosolic dsDNA and the dsDNA serves as oligomerization platform. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing AIM2 are readily searchable from our website. Different antibodies against the same target such as AIM2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. AIM2 also interacts with the following gene(s): CASP1, DDX58, EIF2AK2, NLRC4, NLRP1, NLRP3, PYCARD. The following patways have been known to be associated with this gene. Atherosclerosis, Breast Neoplasms, Disease Models, Animal, Fibrosis, Inflammation, Liver Cirrhosis, Lung Diseases, Necrosis, Nervous System Diseases, Pneumonia are some of the diseases may be linked to AIM2 Antibody BIOTIN-Conjugated. Blood, Bone, Brain, Cervix, Connective Tissue, Intestine, Lung, Lymph Node, Mouth, Spleen tissues are correlated with this protein.