anti-AIM2 antibody product blog
Tags: Antibody; Polyclonal Antibody; AIM2; anti-AIM2 antibody;
The AIM2 aim2 (Catalog #MBS9406630) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AIM2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s AIM2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC).Immunohistochemistry: 1:50-1:200. Researchers should empirically determine the suitability of the AIM2 aim2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The AIM2 aim2 product has the following accession number(s) (GI #4757734) (NCBI Accession #NP_004824.1) (Uniprot Accession #O14862). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the AIM2 Antibody with the following immunoassay(s):
Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/60.)
Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue using at dilution 1/60.)
Interferon-inducible protein AIM2 (Absent in melanoma 2) is a 343 amino acid protein belonging to the HIN-200 family. Induced by IFN-, AIM2 is thought to act as a tumor suppressor by repressing NF B transcriptional activity. Localized to the nucleus, AIM2 contains one DAPIN domain and one HIN-200 domain. The DAPIN domain is composed mostly of -helixes and is a protein-protein interaction domain capable of binding other DAPIN domains. The HIN-200 domain has been shown to bind directly to DNA, which, along with the binding of another protein ASC, results in the activation of Caspase-1.
Immunogen Type: Recombinant Protein
Immunogen Description: Fusion protein corresponding to a region derived from internal residues of human absent in melanoma 2. Target Name: AIM2. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing AIM2 are readily searchable from our website. Different antibodies against the same target such as AIM2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Breast Neoplasms, Central Nervous System Diseases, Disease Models, Animal, Inflammation, Lung Diseases, Lymphoma, Necrosis, Neoplasms, Experimental, Nervous System Diseases, Pneumonia are some of the diseases may be linked to AIM2 Antibody. Blood, Bone, Brain, Cervix, Connective Tissue, Intestine, Lung, Lymph Node, Mouth, Spleen tissues are correlated with this protein. The following patways have been known to be associated with this gene.