anti-AKR1C1 antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-AKR1C1 antibody; AKR1C1 ;
The AKR1C1 akr1c1 (Catalog #MBS2523231) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AKR1C1 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s AKR1C1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC).WB: 1:500-1:2000
IHC: 1:50-1:200. Researchers should empirically determine the suitability of the AKR1C1 akr1c1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The AKR1C1 akr1c1 product has the following accession number(s) (GI #5453543) (NCBI Accession #NP_001344.2). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the AKR1C1 Polyclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of Human liver cancer and breast infiltRative duct tissue, Human fetal brain tissue using AKR1C1 Polyclonal Antibody at dilution of 1:500)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human colon cancer using AKR1C1 Polyclonal Antibody at dilution of 1:30)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human ovarian cancer using AKR1C1 Polyclonal Antibody at dilution of 1:30)
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Immunogen: Synthetic peptide of human AKR1C1
Calculated Molecular Weight: 37kDa. Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing AKR1C1 are readily searchable from our website. Different antibodies against the same target such as AKR1C1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. AKR1C1 also interacts with the following gene(s): CYP1A1, CYP1A2, CYP2B6, EPHX1, HSD17B3.