anti-AKT1/3 antibody product blog
Tags: Antibody; Polyclonal Antibody; AKT1/3; anti-AKT1/3 antibody;
The AKT1/3 akt1 (Catalog #MBS5302104) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s AKT1/3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA).WB: 1:500-1:1000
IHC: 1:50-1:100
ELISA: 1:20000. Researchers should empirically determine the suitability of the AKT1/3 akt1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The AKT1/3 akt1 product has the following accession number(s) (GI #558550189) (NCBI Accession #AHA61681.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the AKT1/3 antibody (Tyr437/434) with the following immunoassay(s):
Immunohistochemistry (IHC) (Immunohistochemistry analysis of paraffin-embedded human brain tissue using AKT1/3 (Phospho-Tyr437/434) antibody.)
Western Blot (WB) (Western blot analysis of extracts from K562 cells, treated with insulin (0.01U/ml, 15mins), using AKT1/3 (Phospho-Tyr437/434) antibody.)
Rabbit polyclonal AKT1/3 antibody (Tyr437/434).
Biological Significance: Since its initial discovery as a proto-oncogene, the serine/threonine kinase Akt (also known as protein kinase B or PKB) has become a major focus of attention because of its critical regulatory role in diverse cellular processes, including cancer progression and insulin metabolism. Cross-Reactivity: Mouse, Rat
Immunogen: AKT1/3 antibody was raised in Rabbit using a synthetic phosphopeptide derived from human AKT1/3 around the phosphorylation site of tyrosine 437 (T-R-YP-F-D) as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing AKT1/3 are readily searchable from our website. Different antibodies against the same target such as AKT1/3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. AKT1/3 also interacts with the following gene(s): FOXO1, FOXO3, GSK3B, HSP90AA1, ILK, MDM2, MTOR, NOS3, PTEN, RICTOR. Blood, Brain, Heart, Kidney, Liver, Lung, Muscle, Nerve, Prostate, Vascular tissues are correlated with this protein. Breast Neoplasms, Colorectal Neoplasms, Heart Diseases, Inflammation, Insulin Resistance, Lung Neoplasms, Necrosis, Neoplasms, Experimental, Nervous System Diseases, Prostatic Neoplasms are some of the diseases may be linked to AKT1/3 antibody (Tyr437/434). The following patways have been known to be associated with this gene.