anti-AKT1 antibody product blog
Tags: Antibody; anti-AKT1 antibody; AKT1; Polyclonal Antibody;
The AKT1 akt1 (Catalog #MBS6000268) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AKT1, phosphorylated (Ser473) (RAC-alpha Serine/Threonine-protein Kinase, Protein Kinase B, PKB, Proto-oncogene c-Akt, RAC-PK-alpha, PKB, RAC) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s AKT1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 0.25ug/ml
Western Blot: 0.25-1ug/ml. Researchers should empirically determine the suitability of the AKT1 akt1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The AKT1 akt1 product has the following accession number(s) (GI #18027298) (NCBI Accession #AAL55732.1) (Uniprot Accession #P31749). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Plays a role as a key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation (By similarity). General protein kinase capable of phosphorylating several known proteins. Phosphorylates TBC1D4. Signals downstream of phosphatidylinositol 3-kinase (PI(3)K) to mediate the effects of various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), insulin and insulin-like growth factor I (IGF-I). Plays a role in glucose transport by mediating insulin-induced translocation of the GLUT4 glucose transporter to the cell surface. Mediates the antiapoptotic effects of IGF-I. Mediates insulin-stimulated protein synthesis by phosphorylating TSC2 at \'Ser-939\' and \'Thr-1462\', thereby activating mTORC1 signaling and leading to both phosphorylation of 4E-BP1 and in activation of RPS6KB1. Promotes glycogen synthesis by mediating the insulin-induced activation of glycogen synthase.
Immunogen: Synthetic phosphopeptide corresponding to 465-479aa from human AKT (KLH). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing AKT1 are readily searchable from our website. Different antibodies against the same target such as AKT1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Blood, Brain, Heart, Kidney, Liver, Lung, Muscle, Nerve, Prostate, Vascular tissues are correlated with this protein.