|The ALPL alpl (Catalog #MBS1490318) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-mouse Alkaline phosphatase, tissue-nonspecific isozyme polyclonal Antibody, FITC reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Alkaline phosphatase can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the ALPL alpl for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ALPL alpl product has the following accession number(s) (GI #116734717) (NCBI Accession #NP_000469.3) (Uniprot Accession #P05186). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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To clarify its physiologic role, alkaline phosphatase (ALP) was examined in normal skin fibroblasts and was shown to be the tissue-nonspecific (TNS) isoenzyme type (as evidenced by heat and inhibition profiles) and to be active toward millimolar concentrations of the putative natural substrates phosphoethanolamine (PEA) and pyridoxal-5\'-phosphate (PLP).
Storage Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate: FITC. Immunogen: Recombinant mouse Alkaline phosphatase, tissue-nonspecific isozyme protein
Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-23430 / sc-30203. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ALPL are readily searchable from our website. Different antibodies against the same target such as ALPL may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Adipose Tissue, Blood, Bone, Brain, Connective Tissue, Embryonic Tissue, Kidney, Liver, Mouth, Skin tissues are correlated with this protein. Calcinosis, Cardiovascular Diseases, Heart Diseases, Hypertrophy, Inflammation, Kidney Diseases, Liver Diseases, Necrosis, Pain, Seizures are some of the diseases may be linked to Rabbit anti-mouse Alkaline phosphatase, tissue-nonspecific isozyme polyclonal Antibody, FITC. ALPL also interacts with the following gene(s): ENPP1, IBSP. The following patways have been known to be associated with this gene.