anti-ALPP antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-ALPP antibody; ALPP;
The ALPP alpp (Catalog #MBS9209597) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ALPP Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s ALPP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC).WB~~1:1000. Researchers should empirically determine the suitability of the ALPP alpp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ALPP alpp product has the following accession number(s) (GI #94721246) (NCBI Accession #NP_001623.3) (Uniprot Accession #P05187). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the ALPP Antibody (Center) with the following immunoassay(s):
Western Blot (WB) (ALPP Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the ALPP antibody detected the ALPP protein (arrow).)
Immunohistochemistry (IHC) (ALPP Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ALPP Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
There are at least four distinct but related alkaline
phosphatases: intestinal, placental, placental-like, and
liver/bone/kidney (tissue non-specific). The first three are
located together on chromosome 2 while the tissue non-specific form
is located on chromosome 1. The product of this gene is a membrane
bound glycosylated enzyme, also referred to as the heat stable
form, that is expressed primarily in the placenta although it is
closely related to the intestinal form of the enzyme as well as to
the placental-like form. The coding sequence for this form of
alkaline phosphatase is unique in that the 3\' untranslated region
contains multiple copies of an Alu family repeat. In addition, this
gene is polymorphic and three common alleles (type 1, type 2 and
type 3) for this form of alkaline phosphatase have been well
characterized.
Antigen Type: Synthetic Peptide. Antigen Source: HUMAN. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ALPP are readily searchable from our website. Different antibodies against the same target such as ALPP may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.