|The ANG1 ang1 (Catalog #MBS1489675) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-Bovine Angiogenin-1 polyclonal Antibody, FITC reacts with Bovine and may cross-react with other species as described in the data sheet. MyBioSource\'s Angiogenin-1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the ANG1 ang1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ANG1 ang1 product has the following accession number(s) (GI #20455472) (NCBI Accession #P10152.4) (Uniprot Accession #P10152). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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May function as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo. Has very low ribonuclease activity.
Storage Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate: FITC. Immunogen: Recombinant Bovine Angiogenin-1 protein. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ANG1 are readily searchable from our website. Different antibodies against the same target such as ANG1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Adipose Tissue, Brain, Embryonic Tissue, Intestine, Kidney, Liver, Lung, Muscle, Ovary, Skin tissues are correlated with this protein. ANG1 also interacts with the following gene(s): RNASE6, RNH1, TARDBP, TEK, VEGFA.