|The APOBEC3A apobec3a (Catalog #MBS9209397) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The APOBEC3A Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s APOBEC3A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA).
WB~~1:1000. Researchers should empirically determine the suitability of the APOBEC3A apobec3a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The APOBEC3A apobec3a product has the following accession number(s) (GI #300869638) (NCBI Accession #NP_001180218.1) (Uniprot Accession #P31941). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the APOBEC3A Antibody (N-term) with the following immunoassay(s):
Western Blot (WB) (APOBEC3A Antibody (N-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the APOBEC3A antibody detected the APOBEC3A protein (arrow).)
This gene is a member of the cytidine deaminase gene
family. It is one of seven related genes or pseudogenes found in a
cluster, thought to result from gene duplication, on chromosome 22.
Members of the cluster encode proteins that are structurally and
functionally related to the C to U RNA-editing cytidine deaminase
APOBEC1. The protein encoded by this gene lacks the zinc binding
activity of other family members. The protein plays a role in
immunity, by restricting transmission of foreign DNA such as
viruses. One mechanism of foreign DNA restriction is deamination of
foreign double-stranded DNA cytidines to uridines, which leads to
DNA degradation. However, other mechanisms are also thought to be
involved, as anti-viral effect is not dependent on deaminase
activity. One allele of this gene results from the deletion of
approximately 29.5 kb of sequence between this gene, APOBEC3A, and
the adjacent gene APOBEC3B. The breakpoints of the deletion are
within the two genes, so the deletion allele is predicted to have
the promoter and coding region of APOBEC3A, but the 3\' UTR of
Antigen Type: Synthetic Peptide. Antigen Source: HUMAN. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing APOBEC3A are readily searchable from our website. Different antibodies against the same target such as APOBEC3A may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.