|The AQP1 aqp1 (Catalog #MBS540989) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Aquaporin 1 Antibody BIOTIN-Conjugated reacts with Bovine, Human, Mouse, Rat, Sheep and may cross-react with other species as described in the data sheet. MyBioSource\'s Aquaporin 1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB).
Western Blot: 1:500. Researchers should empirically determine the suitability of the AQP1 aqp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The AQP1 aqp1 product has the following accession number(s) (GI #19387211) (NCBI Accession #AAL87136) (Uniprot Accession #P29972). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
Immunogen: Synthetic peptide taken within amino acid region 215-265 on human Aquaporin 1 protein.
Expression: Detected in erythrocytes (at protein level). Expressed in a number of tissues including erythrocytes, renal tubules, retinal pigment epithelium, heart, lung, skeletal muscle, kidney and pancreas. Weakly expressed in brain, placenta and liver. Molecular Function: Blood group antigen; Transport
Structure: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
Subcellular Location: Cell membrane; Multi-pass membrane protein. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing AQP1 are readily searchable from our website. Different antibodies against the same target such as AQP1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain, Eye, Heart, Intestine, Kidney, Liver, Lung, Mouth, Muscle, Vascular tissues are correlated with this protein. Adenocarcinoma, Carcinoma, Disease Models, Animal, Edema, Fibrosis, Hypertension, Inflammation, Kidney Diseases, Liver Diseases, Nervous System Diseases are some of the diseases may be linked to Aquaporin 1 Antibody BIOTIN-Conjugated. AQP1 also interacts with the following gene(s): AQP2, AVP, HBB, TNF, UHMK1. The following patways have been known to be associated with this gene.