anti-AQP6 antibody product blog
Tags: Antibody; Polyclonal Antibody; Aquaporin 6; anti-Aqp6 antibody; Aqp6;
The AQP6 aqp6 (Catalog #MBS176041) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Aquaporin 6 antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Aquaporin 6 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin. Researchers should empirically determine the suitability of the AQP6 aqp6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The AQP6 aqp6 product has the following accession number(s) (GI #212276421) (NCBI Accession #Q13520.2) (Uniprot Accession #Q13520). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-Aquaporin 6 antibody with the following immunoassay(s):
Western Blot (WB) (Anti-Aquaporin 6 antibody, MBS176041, Western blotting
Lane 1: U87 Cell Lysate
Lane 2: COLO320 Cell Lysate
Lane 3: MCF-7 Cell Lysate
)
Immunohistochemistry (IHC) (Anti-Aquaporin 6 antibody, MBS176041, IHC(P)
IHC(P): Human Placenta Tissue )
Immunohistochemistry (IHC) (Anti-Aquaporin 6 antibody, MBS176041, IHC(P)
IHC(P): Human Lung Cancer Tissue )
Description: Rabbit IgG polyclonal antibody for Aquaporin-6(AQP6) detection. Tested with WB, IHC-P in Human.
Background: Aquaporin 6, kidney specific is a protein in humans that is encoded by the AQP6 gene. The aquaporins(AQPs) are a family of water-transporting proteins that facilitate osmotically driven water movement across cell plasma membranes. Among the seven human aquaporins cloned to date(AQPs 0-6), genes encoding the four most closely related aquaporins(AQP0, AQP2, AQP5, and AQP6) have been mapped to chromosome band 12q13, suggesting an aquaporin family gene cluster at this locus. Unlike other aquaporins, AQP6 functions not as a water channel but as an anion-selective channel. Single-channel analyses have shown AQP6 to flicker rapidly between closed and open status.
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Aquaporin 6 (264-282aa EPLKKESQPGSGAVEMESV). Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing AQP6 are readily searchable from our website. Different antibodies against the same target such as AQP6 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.