|The ARHGEF26 arhgef26 (Catalog #MBS6013565) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SGEF, ID (ARHGEF26, SGEF, Rho guanine nucleotide exchange factor 26, SH3 domain-containing guanine exchange factor) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s SGEF can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC).
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:10-50. Researchers should empirically determine the suitability of the ARHGEF26 arhgef26 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ARHGEF26 arhgef26 product has the following accession number(s) (GI #16741655) (NCBI Accession #AAH16628.1) (Uniprot Accession #Q96DR7). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
SGEF activates RhoG GTPase by promoting the exchange of GDP by GTP. Required for the formation of membrane ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB, which induces cytoskeleton rearrangements and promotes bacterial entry.
Immunogen: SGEF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 377-406 amino acids from the Central region of human SGEF. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ARHGEF26 are readily searchable from our website. Different antibodies against the same target such as ARHGEF26 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Atherosclerosis, Disease Models, Animal, Inflammation are some of the diseases may be linked to SGEF, ID (ARHGEF26, SGEF, Rho guanine nucleotide exchange factor 26, SH3 domain-containing guanine exchange factor).