anti-ARHGEF5 antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-ARHGEF5 antibody; ARHGEF5;
The ARHGEF5 arhgef5 (Catalog #MBS7045879) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ARHGEF5 Antibody, HRP conjugated reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s ARHGEF5 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the ARHGEF5 arhgef5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The ARHGEF5 arhgef5 product has the following accession number(s) (GI #50959191) (NCBI Accession #NP_005426.2) (Uniprot Accession #Q12774). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Guanine nucleotide exchange factor which activates Rho GTPases (PubMed:15601624). Strongly activates RHOA (PubMed:15601624). Also strongly activates RHOB, weakly activates RHOC and RHOG and shows no effect on RHOD, RHOV, RHOQ or RAC1 (By similarity). Involved in regulation of cell shape and actin cytoskeletal organization (PubMed:15601624). Plays a role in actin organization by generating a loss of actin stress fibers and the formation of membrane ruffles and filopodia (PubMed:14662653). Required for SRC-induced podosome formation (By similarity). Involved in positive regulation of immature dendritic cell migration (By similarity).
Species: Human
Immunogen: Recombinant human Rho guanine nucleotide exchange factor 5 protein. Conjugate: HRP
Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ARHGEF5 are readily searchable from our website. Different antibodies against the same target such as ARHGEF5 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Bone, Bone Marrow, Brain, Kidney, Lung, Mouth, Skin tissues are correlated with this protein. Adenocarcinoma, Brain Diseases, Breast Neoplasms, Cell Transformation, Neoplastic, Disease Models, Animal, Inflammation are some of the diseases may be linked to ARHGEF5 Antibody, HRP conjugated.