anti-ARHGEF7 antibody product blog
Tags: Antibody; Polyclonal Antibody; ARHGEF7; anti-ARHGEF7 antibody;
The ARHGEF7 arhgef7 (Catalog #MBS2522664) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ARHGEF7 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s ARHGEF7 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC).WB: 1:500-1:2000
IHC: 1:50-1:200. Researchers should empirically determine the suitability of the ARHGEF7 arhgef7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ARHGEF7 arhgef7 product has the following accession number(s) (GI #54304008) (NCBI Accession #CAH59949.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the ARHGEF7 Polyclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of Human brain malignant glioma tissue, A172 and 293T cell using ARHGEF7 Polyclonal Antibody at dilution of 1:800)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human gastic cancer using ARHGEF7 Polyclonal Antibody at dilution of 1:40)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human thyroid cancer using ARHGEF7 Polyclonal Antibody at dilution of 1:40)
Rho GTPases play a fundamental role in numerous cellular processes triggered by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. This protein can induce membrane ruffling. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Immunogen: Recombinant protein of human ARHGEF7
Calculated Molecular Weight: 90kDa. Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ARHGEF7 are readily searchable from our website. Different antibodies against the same target such as ARHGEF7 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Bone, Bone Marrow, Brain, Heart, Kidney, Lung, Ovary, Stomach, Vascular tissues are correlated with this protein. The following patways have been known to be associated with this gene. Brain Diseases, Cardiovascular Diseases, Disease Models, Animal, Inflammation, Kidney Diseases, Nervous System Diseases, Nervous System Malformations, Neurobehavioral Manifestations are some of the diseases may be linked to ARHGEF7 Polyclonal Antibody.