anti-ARL1 antibody product blog
Tags: Antibody; Polyclonal Antibody; ARL1; anti-Arl1 antibody;
The ARL1 arl1 (Catalog #MBS628791) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ARL1, NT (ADP-ribosylation Factor-like Protein 1) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s ARL1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC).Suitable for use in ELISA, Western Blot, and Immunohistochemistry.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-1:500
Immunohistochemistry: 1:50-1:100. Researchers should empirically determine the suitability of the ARL1 arl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ARL1 arl1 product has the following accession number(s) (GI #4502227) (NCBI Accession #NP_001168.1) (Uniprot Accession #P40616). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the ARL1, NT (ADP-ribosylation Factor-like Protein 1) with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of hARL1-G3 in K562 cell line lysates (35ug/lane). ARL1 (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC) (Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
ARL1 belongs to the ARL (ADP-ribosylation factor-like) family of proteins, which are structurally related to ADP-ribosylation factors (ARFs). ARFs, described as activators of cholera toxin (CT) ADP-ribosyltransferase activity, regulate intracellular vesicular membrane trafficking, and stimulate a phospholipase D (PLD) isoform. Although, ARL proteins were initially thought not to activate CT or PLD, later work showed that they are weak stimulators of PLD and CT in a phospholipid dependent manner.
Immunogen: Synthetic peptide selected from the N-terminal region of human ARL1 (KLH). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ARL1 are readily searchable from our website. Different antibodies against the same target such as ARL1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Drug Toxicity, Kidney Diseases are some of the diseases may be linked to ARL1, NT (ADP-ribosylation Factor-like Protein 1).