|The ARTN artn (Catalog #MBS616173) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Artemin, NT (GFRalpha3-RET Ligand) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Artemin can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).
Suitable for use in Western Blot and ELISA.,, Recommended Dilution:, Western blot: 1:250 to 1:500, Optimal dilutions to be determined by the researcher. Researchers should empirically determine the suitability of the ARTN artn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ARTN artn product has the following accession number(s) (GI #4235100) (Uniprot Accession #Q5T4W7). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Artemin is a novel member of the GDNF family and demonstrated that it is the ligand for the former orphan receptor GFRalpha3-RET. Artemin is a survival factor for sensory and sympathetic neurons in culture, and its expression pattern suggests that it also in uences these neurons in vivo. Artemin can also activate the GFRalpha1-RET complex and supports the survival of dopaminergic midbrain neurons in culture.
Immunogen: N terminus of Artemin. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ARTN are readily searchable from our website. Different antibodies against the same target such as ARTN may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Adenocarcinoma, Breast Neoplasms, Carcinoma, Congenital Abnormalities, Female Urogenital Diseases, Hyperalgesia, Inflammation, Melanoma, Neoplasm Metastasis, Spinal Cord Injuries are some of the diseases may be linked to Artemin, NT (GFRalpha3-RET Ligand). The following patways have been known to be associated with this gene. Brain, Esophagus, Intestine, Kidney, Lung, Pancreas tissues are correlated with this protein. ARTN also interacts with the following gene(s): GFRA3.