anti-ASPP1 antibody product blog
Tags: Antibody; Polyclonal Antibody; ASPP1; anti-ASPP1 antibody;
The ASPP1 ppp1r13b (Catalog #MBS2516921) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ASPP1 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s ASPP1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC).IHC: 1:25-1:100. Researchers should empirically determine the suitability of the ASPP1 ppp1r13b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ASPP1 ppp1r13b product has the following accession number(s) (GI #121114287) (NCBI Accession #NP_056131.2). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the ASPP1 Polyclonal Antibody with the following immunoassay(s):
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human liver cancer tissue using ASPP1 Polyclonal Antibody at dilution 1:35)
The protein plays a central role in regulation of apoptosis via its interaction with p53/TP53. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. It contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins.
Immunogen: Synthetic peptide of human ASPP1. Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ASPP1 are readily searchable from our website. Different antibodies against the same target such as ASPP1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Adenocarcinoma, Breast Neoplasms, Carcinoma, Hepatocellular, Edema, Embryo Loss, Liver Neoplasms, Neoplasm Metastasis are some of the diseases may be linked to ASPP1 Polyclonal Antibody. ASPP1 also interacts with the following gene(s): BAX, EP300, LATS1, LATS2, TP53, TP63. Embryonic Tissue, Eye, Kidney, Liver, Lung, Lymph Node, Placenta, Skin, Uterus, Vascular tissues are correlated with this protein.