anti-ATF2 antibody product blog
Tags: Antibody; ATF2; anti-ATF2 antibody; Polyclonal Antibody;
The ATF2 atf2 (Catalog #MBS6011181) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ATF2, phosphorylated (pS480) (Cyclic AMP-dependent transcription factor ATF-2, Activating transcription factor 2, cAMP response element-binding protein CRE-BP1, HB16, CREB2, CREBP1) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s ATF2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).Suitable for use in ELISA, Western Blot
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500. Researchers should empirically determine the suitability of the ATF2 atf2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ATF2 atf2 product has the following accession number(s) (GI #78070398) (NCBI Accession #AAI07699.1) (Uniprot Accession #P15336). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
ATF2 is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components.
Immunogen: Phospho-ATF2-pS480 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S480 of human ATF2. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ATF2 are readily searchable from our website. Different antibodies against the same target such as ATF2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Blood, Bone, Brain, Kidney, Liver, Lung, Muscle, Nerve, Skin, Vascular tissues are correlated with this protein. Brain Diseases, Breast Neoplasms, Cardiovascular Diseases, Disease Models, Animal, Inflammation, Necrosis, Neoplasms, Neoplasms, Experimental, Nervous System Diseases, Skin Diseases are some of the diseases may be linked to ATF2, phosphorylated (pS480) (Cyclic AMP-dependent transcription factor ATF-2, Activating transcription factor 2, cAMP response element-binding protein CRE-BP1, HB16, CREB2, CREBP1).