anti-atf4b2 antibody product blog
Tags: Antibody; Polyclonal Antibody; Activating Transcription Factor 4; anti-atf4b2 antibody; atf4b2;
The atf4b2 n/a (Catalog #MBS631150) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Activating Transcription Factor 4, phosphorylated (Ser245) (ATF4, Tax-responsive Enhancer Element B67, Cyclic AMP-dependent Transcription Factor ATF-4, cAMP-dependent Transcription Factor ATF-4, Cyclic AMP-responsive Element-binding Protein 2, CREB-2, cAM reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Activating Transcription Factor 4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Immunohistochemistry (IHC).Suitable for use in ELISA and Immunohistochemistry.
Dilution: ELISA:1:10,000
Immunohistochemistry:1:50-1:100. Researchers should empirically determine the suitability of the atf4b2 n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The atf4b2 n/a product has the following accession number(s) (GI #157073893) (NCBI Accession #NP_001096662.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
ATF4 is a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). ATF4 belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain.
Immunogen: Synthetic phosphopeptide corresponding to human ATF4 around the phosphorylation site of Serine 245. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing atf4b2 are readily searchable from our website. Different antibodies against the same target such as atf4b2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Bone, Brain, Connective Tissue, Ear, Embryonic Tissue, Heart, Kidney, Muscle, Umbilical Cord, Vascular tissues are correlated with this protein. The following patways have been known to be associated with this gene.