anti-ATG10 antibody product blog
Tags: Antibody; Polyclonal Antibody; ATG10; anti-ATG10 antibody; Apg10;
The ATG10 atg10 (Catalog #MBS621088) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Apg10 (Autophagy-related Protein 10, Autophagy 10-like, APG10-like, Atg10) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s Apg10 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).Suitable for use in Western Blot.
Dilution: Western Blot: 0.5-1ug/ml. Researchers should empirically determine the suitability of the ATG10 atg10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ATG10 atg10 product has the following accession number(s) (GI #18594496) (NCBI Accession #NP_113670.1) (Uniprot Accession #Q9H0Y0). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Apg10 (Autophagy-related Protein 10, Autophagy 10-like, APG10-like, Atg10) with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of ATG10 in SK-N-SH cell lysate with ATG10 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml.)
Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnAnother member of the autophagy protein family is ATG10, an E2-like enzyme involved in two ubiquitin-like modifications essential for autophagosome formation: ATG12-ATG5 conjugation and the modification of a soluble form of MAP-LC3, a homolog of yeast Apg8, to a membrane-bound form (4). ATG10 has also been shown to interact with ATG12 in human embryonic kidney cells in the presence of ATG7 (4). Multiple isoforms of ATG10 are known to exist.
Immunogen: Synthetic peptide corresponding to 15aa from near the carboxy terminus of human ATG10 (Genbank accession No. EAW95884). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ATG10 are readily searchable from our website. Different antibodies against the same target such as ATG10 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. ATG10 also interacts with the following gene(s): ATG12, ATG5, ATG7.