anti-ATOH8 antibody product blog
Tags: Antibody; Polyclonal Antibody; ATOH8; anti-ATOH8 antibody;
The ATOH8 atoh8 (Catalog #MBS9406546) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ATOH8 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s ATOH8 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the ATOH8 atoh8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The ATOH8 atoh8 product has the following accession number(s) (GI #226498192) (NCBI Accession #NP_116216). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the ATOH8 Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of ATOH8 in A-20 cell lysate with ATOH8 antibody at (A) 1 and (B) 2 ug/mL.)
Immunohistochemistry (IHC) (Immunohistochemistry of ATOH8 in mouse brain tissue with ATOH8 antibody at 5 ug/mL.)
Basic helix-loop-helix (bHLH) transcription factors play important roles in differentiation processes during embryonic development of vertebrates. ATOH8 (MATH6) is a tissue-restricted member of the atonal superfamily of bHLH transcription factors that exhibits 43-57% identity in the bHLH domain with other mammalian atonal paralogs including the NeuroD and Neurogenin factors. In the mouse, ATOH8 has been implicated in the specification and differentiation of neuronal cell lineages in the brain and may also participate in kidney development. Recent studies show that ATOH8 is a novel component of the pancreatic transcriptional network during embryonic development and suggest a potential role as a modulator of the differentiation program initiated by the pro-endocrine factor Neurog3. It is indispensable for early embryonic development, suggesting a more widespread function for this factor in tissue-specific differentiation processes that are dependent on class II bHLH genes.
Immunogen Type: Peptide
Immunogen Description: Raised against a 15 amino acid peptide near the carboxy terminus of human ATOH8. Target Name: ATOH8. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ATOH8 are readily searchable from our website. Different antibodies against the same target such as ATOH8 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Bladder, Brain, Embryonic Tissue, Eye, Kidney, Liver, Muscle, Vascular tissues are correlated with this protein.