|The BAI1 bai1 (Catalog #MBS395944) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Brain-Specific Angiogenesis Inhibitor 1 (BAI1) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Brain-Specific Angiogenesis Inhibitor 1 (BAI1) can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the BAI1 bai1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The BAI1 bai1 product has the following accession number(s) (GI #111118994) (NCBI Accession #NP_001693.2) (Uniprot Accession #O14514). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Brain-Specific Angiogenesis Inhibitor 1 (BAI1) with the following immunoassay(s):
Immunohistochemistry (IHC) (BAI1 staining of formallin fixed paraffin embedded human brain tissue at a dilution of 20 ug/ml. Antigen retrieval using a citrate buffer and steam/heat was utilized.)
BAI1 is an Orphan-B GPCR with an unknown ligand. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis, and a growth suppressor of glioblastoma. Along with BAI1, there are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3, which have similar tissue specificities and structures. However, only BAI1 is transcriptionally regulated by p53. Loss of BAI1 expression has been implicated in glioblastoma.
Immunogen: N-terminal domain of human. Positive Control: Human brain tissue. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing BAI1 are readily searchable from our website. Different antibodies against the same target such as BAI1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain Diseases, Disease Models, Animal, Inflammation, Kidney Diseases, Necrosis, Nervous System Diseases are some of the diseases may be linked to Brain-Specific Angiogenesis Inhibitor 1 (BAI1). Brain, Lung, Nerve tissues are correlated with this protein. BAI1 also interacts with the following gene(s): BAIAP2, MAGI1, PHYHIP, TP53. The following patways have been known to be associated with this gene.