|The Bak bak1 (Catalog #MBS9409316) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Bak Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Bak can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF).
Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100. Researchers should empirically determine the suitability of the Bak bak1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The Bak bak1 product has the following accession number(s) (GI #4502363) (NCBI Accession #NP_001179.1) (Uniprot Accession #Q16611). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Bak Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of extracts from 293 cells, using Bak antibody.)
Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human skeletal muscle tissue using Bak antibody.)
In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti-apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis.Takuma Uo, J. Biol. Chem., Mar 2005; 280: 9065 - 9073.Pierre-Fran ois Cartron, Mol. Cell. Biol., Jul 2003; 23: 4701 - 4712.Joslyn K. Brunelle, J. Biol. Chem., Feb 2004; 279: 4305 - 4312.Neil A. Jones, Mol. Pharmacol., May 1998; 53: 819.
Immunogen Type: Peptide
Immunogen Description: Synthesized peptide derived from human Bak. Target Name: Bak. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Bak are readily searchable from our website. Different antibodies against the same target such as Bak may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain Diseases, Breast Neoplasms, Colonic Neoplasms, Gastrointestinal Diseases, Inflammation, Lung Neoplasms, Necrosis, Neoplasms, Experimental, Nervous System Diseases, Prostatic Neoplasms are some of the diseases may be linked to Bak Antibody. Bak also interacts with the following gene(s): APAF1, BAX, BCL2A1, BCL2L1, BID, MCL1, TP53, VDAC1, VDAC2. Blood, Bone, Bone Marrow, Brain, Intestine, Kidney, Liver, Lung, Prostate, Vascular tissues are correlated with this protein. The following patways have been known to be associated with this gene.