|The BAX bax (Catalog #MBS9214479) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Bax Antibody (Center) reacts with Human (Predicted Reactivity: Mouse, Rat) and may cross-react with other species as described in the data sheet. MyBioSource\'s Bax can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA).
WB~~1:1000. Researchers should empirically determine the suitability of the BAX bax for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The BAX bax product has the following accession number(s) (GI #4757838) (NCBI Accession #NP_004315.1) (Uniprot Accession #Q07812). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Bax Antibody (Center) with the following immunoassay(s):
Western Blot (WB) (Bax Antibody western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the Bax antibody detected the Bax protein (arrow).)
The protein encoded by this gene belongs to the BCL2
protein family. BCL2 family members form hetero- or homodimers and
act as anti- or pro-apoptotic regulators that are involved in a
wide variety of cellular activities. This protein forms a
heterodimer with BCL2, and functions as an apoptotic activator.
This protein is reported to interact with, and increase the opening
of, the mitochondrial voltage-dependent anion channel (VDAC), which
leads to the loss in membrane potential and the release of
cytochrome c. The expression of this gene is regulated by the tumor
suppressor P53 and has been shown to be involved in P53-mediated
apoptosis. Multiple alternatively spliced transcript variants,
which encode different isoforms, have been reported for this gene.
Antigen Type: Synthetic Peptide. Antigen Source: HUMAN. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing BAX are readily searchable from our website. Different antibodies against the same target such as BAX may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain Diseases, Breast Neoplasms, Heart Diseases, Inflammation, Intestinal Neoplasms, Ischemia, Liver Diseases, Necrosis, Neoplasms, Experimental, Nervous System Diseases are some of the diseases may be linked to Bax Antibody (Center). Blood, Bone, Brain, Eye, Liver, Lung, Nerve, Prostate, Skin, Stomach tissues are correlated with this protein.