|The BD3 defb3 (Catalog #MBS536148) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BD3 antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s BD3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).
WB: 1:500-1:1,000. Researchers should empirically determine the suitability of the BD3 defb3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The BD3 defb3 product has the following accession number(s) (GI #7304997) (NCBI Accession #NP_038784.1) (Uniprot Accession #Q9WTL0). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Affinity purified Rabbit polyclonal BD3 antibody.
Biological Significance: A novel, nonhemolytic antimicrobial peptide (human beta-defensin-3, hBD-3) was isolated from human lesional psoriatic scales and cloned from keratinocytes. hBD-3 demonstrated a salt-insensitive broad spectrum of potent antimicrobial activity against many potentially pathogenic microbes including multiresistant S. aureus and vancomycin-resistant Enterococcus faecium. Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
Immunogen: BD3 antibody was raised in rabbit using residues 23-33 [GIINTLQKYYC] of the 5-kDa human beta-defensin-3 protein as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing BD3 are readily searchable from our website. Different antibodies against the same target such as BD3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. BD3 also interacts with the following gene(s): Defb1, Defb14, Defb2, S100a8.